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Jan 26, 2023
Psychological and emotional distress among childhood cancer survivors influencing risky lifestyle behaviors
Life after cancer for many survivors entails following a care plan to stay healthy – both physically and emotionally. But for young adult survivors of childhood cancer, their care plan can be more complex as they navigate adulthood and the risks of developing other health issues over their lifespan. The reported prevalence of cancer-related cognitive impairment (CRCI) ranges between 10% and 40% among childhood, adolescent, and young adult cancer survivors. CRCI afflicts survivors with emotional and social dysfunction and this can negatively impact their employment, education and independent living.
Jan 11, 2023
Two faculty members awarded pilot funding for new projects to confront extremism through community, thriving and wellness
In recognition of their evidence-based research strategies to enhance best practices for community engagement and foster improvements in the aftermath of COVID-19, the UCI Office of Inclusive Excellence has awarded pilot funding to Sora Park Tanjasiri, DrPH, a professor of epidemiology and biostatistics and Alana LeBrón, PhD, an assistant professor of health, society, and behavior.
Nov 17, 2022
Five UCI faculty members make list of world’s top female scientists
Research.com’s first ranking of the top 1,000 female scientists in the world includes five UCI faculty members. Susan O'Brien, Associate Director for Clinical Science for the Chao Family Comprehensive Cancer Center has been included on this list. According to Research.com, the aim of this ranking is to inspire female scholars, women considering academic careers and decision-makers worldwide with examples of successful women in the scientific community. The rankings were created with the aim that they will help provide more opportunities, visibility and equal chances for women in science.
Aug 10, 2022 | UCI School of Medicine
New UCI-led research reveals the circadian clock influences cell growth, metabolism and tumor progression
In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression. Their research also reveals how disruption of the circadian clock impacts genome stability and mutations that can further drive critical tumor promoting pathways in the intestine.
New UCI-led study reveals computation-guided approach to suppressing cancer tumor growth
A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers. This approach was successful both in vitro and in vivo. This strategy can increase chemical diversity of p53 corrector molecules for clinical development.
Jul 11, 2022
‘A window into the body’
The so-called “diagnostic fluid of the future,” saliva is loaded with DNA, enzymes, hormones, immune system markers and other substances that make it a minimally invasive alternative biospecimen to blood for a dizzying array of medical, nonmedical and even commercial uses. However, expertise is required to decipher biomarkers, many clinicians still do not collect saliva samples, and “spit science” research can literally be all over the map. That’s where UCI’s Institute for Interdisciplinary Salivary Bioscience Research comes in. Co-directed by Jenna Riis, assistant professor of psychological science, and Michael Hoyt, a clinical and health psychologist and associate professor of population health and disease prevention, the IISBR conducts salivary bioscience research and educates, trains and consults researchers, physicians, caregivers, veterinarians, psychologists and other professionals on collecting and analyzing spit samples.
Jun 24, 2022
Elizabeth Brem, MD, on Frontline Management of CLL
In the last few years, frontline management of chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) has undergone a profound paradigm shift. First-line treatment with novel targeted therapies has become preferable to the use of chemoimmunotherapy regimens such as fludarabine, cyclophosphamide, and rituximab (FCR) -- the latter being largely reserved for patients younger than 65 with no comorbidities, and no 17p deletion or other TP53 mutations.
Jun 06, 2022
Melanoma researcher covers all the bases
Dr. Anand Ganesan probably won’t be hanging from a ceiling `a la Tom Cruise in Mission Impossible, but the UCI Health dermatologist and School of Medicine professor of dermatology and biological sciences does compare part of what he does to a plot device in the 1996 action thriller.
Apr 29, 2022
UCI researchers harness the power of mathematical modeling to understand the effectiveness of aspirin on colorectal cancer prevention
Aspirin can significantly reduce the incidence of colorectal cancer, and this protection can be the result of changed evolutionary processes of cells within patients, according to mathematical models produced by UCI researchers and partners. Results from the study were published in eLife Sciences.
Jan 26, 2022
UCI and CSU Fullerton partner to advance cancer health disparities research with a focus on diversity and inclusion
With a grant of more than $1.1 million from the National Cancer Institute (NCI), the UCI Chao Family Comprehensive Cancer Center (CFCCC) and California State University, Fullerton (CSUF) have established a collaborative partnership focused on addressing cancer disparities of the highest need in Orange County.